3KYS

Crystal structure of human YAP and TEAD complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Transcriptional enhancer factor TEF-1	polymer	219	25676.4	2	UniProt (P28347) Pfam (PF17725) In PDB	Homo sapiens (Human)	NTEF-1,Protein GT-IIC,TEA domain family member 1,TEAD-1,Transcription factor 13,TCF-13
2	B, D	65 kDa Yes-associated protein	polymer	125	13164.7	2	UniProt (P46937) In PDB	Homo sapiens (Human)	ranscriptional coactivator YAP1,Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog
3		water	water		18.0	52	Chemie (HOH)

Sequence modifications

A, C: 194 - 411 (UniProt: P28347)

PDB	External Database	Details
Met 193	-	expression tag

B, D: 50 - 171 (UniProt: P46937)

PDB	External Database	Details
Ser 47	-	expression tag
His 48	-	expression tag
Met 49	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77682.2
All*	Total formula weight	77682.2

*Water molecules are not included.