3KYS
Crystal structure of human YAP and TEAD complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Transcriptional enhancer factor TEF-1 | polymer | 219 | 25676.4 | 2 | UniProt (P28347) Pfam (PF17725) | Homo sapiens (Human) | NTEF-1,Protein GT-IIC,TEA domain family member 1,TEAD-1,Transcription factor 13,TCF-13 |
| 2 | B, D (B, D) | 65 kDa Yes-associated protein | polymer | 125 | 13164.7 | 2 | UniProt (P46937) Pfam (PF15238) | Homo sapiens (Human) | ranscriptional coactivator YAP1,Yes-associated protein 1,Protein yorkie homolog,Yes-associated protein YAP65 homolog |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, C: 194 - 411 (UniProt: P28347)
B, D: 50 - 171 (UniProt: P46937)
| PDB | External Database | Details |
|---|---|---|
| Met 193 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 47 | - | expression tag |
| His 48 | - | expression tag |
| Met 49 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 77682.2 | |
| All* | Total formula weight | 77682.2 |
