3KXX

Structure of the mutant Fibroblast Growth Factor receptor 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Basic fibroblast growth factor receptor 1	polymer	317	36198.5	4	UniProt (P11362) Pfam (PF07714)	Homo sapiens (human)	FGFR-1, bFGF-R, Fms-like tyrosine kinase 2, c-fgr

Sequence modifications

A, B, C, D: 458 - 765 (UniProt: P11362)

PDB	External Database	Details
Met 449	-	expression tag
Gly 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag
His 453	-	expression tag
His 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
Met 457	-	expression tag
Ala 488	Cys 488	engineered mutation
Glu 577	Arg 577	engineered mutation
Ser 584	Cys 584	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	144794.1
All*	Total formula weight	144794.1

*Water molecules are not included.