3KWB
Structure of CatK covalently bound to a dioxo-triazine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (X, Y) | Cathepsin K | polymer | 215 | 23523.5 | 2 | UniProt (P43235) Pfam (PF00112) | Homo sapiens (human) | Cathepsin O, Cathepsin X, Cathepsin O2 |
| 2 | C, D (X, Y) | 3,5-dioxo-4-(3-piperidin-1-ylpropyl)-2-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile | non-polymer | 407.4 | 2 | Chemie (ORH) | |||
| 3 | E, F (X, Y) | water | water | 18.0 | 616 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47047.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 814.8 | |
| All* | Total formula weight | 47861.7 |
