3KUH
Crystal structure of E. coli HPPK(H115A) in complex with AMPCPP and HP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | polymer | 158 | 17899.5 | 1 | UniProt (P26281) Pfam (PF01288) | Escherichia coli | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK |
| 2 | B (A) | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 1 | Chemie (APC) | |||
| 3 | C (A) | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE | non-polymer | 195.2 | 1 | Chemie (PH2) | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | G (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 7 | H (A) | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence modifications
A: 1 - 158 (UniProt: P26281)
| PDB | External Database | Details |
|---|---|---|
| Ala 115 | His 116 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17899.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 843.5 | |
| All* | Total formula weight | 18743.0 |
