3KS9
Metabotropic glutamate receptor mGluR1 complexed with LY341495 antagonist
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Metabotropic glutamate receptor 1 | polymer | 496 | 55689.1 | 2 | UniProt (Q13255) Pfam (PF01094) In PDB | Homo sapiens (human) | mGluR1 |
2 | A, B | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine | non-polymer | 353.4 | 2 | Chemie (Z99) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
5 | water | water | 18.0 | 651 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 518 (UniProt: Q13255)
PDB | External Database | Details |
---|---|---|
Ser 254 | Cys 254 | engineered mutation |
Leu 519 | - | expression tag |
Val 520 | - | expression tag |
Pro 521 | - | expression tag |
Arg 522 | - | expression tag |
Gly 523 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 111378.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1197.8 | |
All* | Total formula weight | 112576.1 |