3KR5

Structure of a protease 4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	M17 leucyl aminopeptidase	polymer	528	58709.0	12	UniProt (Q8IL11) Pfam (PF00883)	Plasmodium falciparum	Malarial protease
2	AC, AD, BB, CA, IC... (I, L, F, C, J...)	CARBONATE ION	non-polymer		60.0	12	Chemie (CO3)
3	BC, BD, CB, CC, CD... (I, L, F, C, J...)	ZINC ION	non-polymer		65.4	24	Chemie (ZN)
4	DC, DD, EB, FA, LC... (I, L, F, C, J...)	(2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid	non-polymer		361.4	12	Chemie (BEY)
5	EC, ED, FB, GA, MC... (I, L, F, C, J...)	SULFATE ION	non-polymer		96.1	15	Chemie (SO4)
6	AA, AB, BA, FC, FD... (B, E, I, L, F...)	PENTAETHYLENE GLYCOL	non-polymer		238.3	37	Chemie (1PE)
7	ID, JD, KD, LD, MD... (A, B, C, D, E...)	water	water		18.0	2314	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 84 - 605 (UniProt: Q8IL11)

PDB	External Database	Details
Gln 152	Asn 152	engineered mutation
Gln 515	Asn 515	engineered mutation
Gln 546	Asn 546	engineered mutation
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	704507.7
Non-Polymers*	Number of molecules	100
	Total formula weight	16883.6
All*	Total formula weight	721391.3

*Water molecules are not included.