3KR4

Structure of a protease 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	M17 leucyl aminopeptidase	polymer	528	58709.0	12	UniProt (Q8IL11) Pfam (PF00883)	Plasmodium falciparum	Malarial protease
2	AC, AD, BB, DA, HC... (I, L, F, C, J...)	CARBONATE ION	non-polymer		60.0	12	Chemie (CO3)
3	BC, CB, EA, IC, KA... (I, F, C, J, D...)	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
4	BD, CC, DB, FA, JC... (L, I, F, C, J...)	2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID	non-polymer		308.4	12	Chemie (BES)
5	CD, DC, EB, GA, KC... (L, I, F, C, J...)	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
6	DD, FB, LC, MC, NA... (L, F, J, D, G...)	SULFATE ION	non-polymer		96.1	14	Chemie (SO4)
7	AA, AB, BA, CA, EC... (B, E, I, L, F...)	PENTAETHYLENE GLYCOL	non-polymer		238.3	37	Chemie (1PE)
8	HD, ID, JD, KD, LD... (A, B, C, D, E...)	water	water		18.0	4858	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 84 - 605 (UniProt: Q8IL11)

PDB	External Database	Details
Gln 152	Asn 152	engineered mutation
Gln 515	Asn 515	engineered mutation
Gln 546	Asn 546	engineered mutation
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	704507.7
Non-Polymers*	Number of molecules	99
	Total formula weight	15658.3
All*	Total formula weight	720166.0

*Water molecules are not included.