3KR0
Crystal Structure of hPNMT in Complex AdoHcy and 2-amino-1H-benzo[d]imidazol-6-ol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Phenylethanolamine N-methyltransferase | polymer | 289 | 31846.0 | 2 | UniProt (P11086) Pfam (PF01234) In PDB | Homo sapiens (human) | PNMTase, Noradrenaline N-methyltransferase |
2 | A, B | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
3 | A, B | 2-AMINO-5-HYDROXY-BENZIMIDAZOLE | non-polymer | 149.2 | 2 | Chemie (172) | |||
4 | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 282 (UniProt: P11086)
PDB | External Database | Details |
---|---|---|
Glu 283 | - | expression tag |
His 284 | - | expression tag |
His 285 | - | expression tag |
His 286 | - | expression tag |
His 287 | - | expression tag |
His 288 | - | expression tag |
His 289 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 63691.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1067.1 | |
All* | Total formula weight | 64759.1 |