3KQZ

Structure of a protease 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	M17 leucyl aminopeptidase	polymer	528	58709.0	12	UniProt (Q8IL11) Pfam (PF00883)	Plasmodium falciparum	Malarial protease
2	DA, ED, FC, LB, LC... (C, K, H, F, I...)	CARBONATE ION	non-polymer		60.0	12	Chemie (CO3)
3	AB, BB, EA, FA, FD... (E, C, K, H, F...)	ZINC ION	non-polymer		65.4	24	Chemie (ZN)
4	AA, CB, DB, EB, GA... (B, E, C, K, H...)	SULFATE ION	non-polymer		96.1	27	Chemie (SO4)
5	AC, AD, AE, BC, BD... (G, J, L, B, E...)	PENTAETHYLENE GLYCOL	non-polymer		238.3	53	Chemie (1PE)
6	BA, JC, TB (B, H, F)	NONAETHYLENE GLYCOL	non-polymer		414.5	3	Chemie (2PE)
7	BE, CE, DE, EE, FE... (A, B, C, D, E...)	water	water		18.0	2523	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 84 - 605 (UniProt: Q8IL11)

PDB	External Database	Details
Gln 152	Asn 152	engineered mutation
Gln 515	Asn 515	engineered mutation
Gln 546	Asn 546	engineered mutation
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	704507.7
Non-Polymers*	Number of molecules	119
	Total formula weight	18755.8
All*	Total formula weight	723263.5

*Water molecules are not included.