3KQK

Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Serine protease/NTPase/helicase NS3	polymer	436	46671.0	2	UniProt (Q9WMX2) Pfam (PF07652) Pfam (PF22027)	Hepatitis C virus (HCV)	Core protein p21, Capsid protein C, p21, Core protein p19, Envelope glycoprotein E1, gp32, gp35, Envelope glycoprotein E2, NS1, gp68, gp70, p7, Protease NS2-3, p23, Serine protease/NTPase/helicase NS3, Hepacivirin, NS3P, p70, Non-structural protein 4A, NS4A, p8, Non-structural protein 4B, NS4B, p27, Non-structural protein 5A, NS5A, p56, RNA-directed RNA polymerase, NS5B, p68
2	C, D (C, D)	5'-D(*TP*TP*TP*TP*TP*T)-3'	polymer	6	1780.2	2
3	E, F, G, H (A, B, C, D)	water	water		18.0	138	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	96902.4
All*	Total formula weight	96902.4

*Water molecules are not included.