3KPE
Solution structure of the respiratory syncytial virus (RSV)six-helix bundle complexed with TMC353121, a small-moleucule inhibitor of RSV
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fusion glycoprotein F0 | polymer | 51 | 5540.5 | 1 | UniProt (P03420) | Human respiratory syncytial virus | Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1 |
| 2 | B (B) | Fusion glycoprotein F0 | polymer | 39 | 4366.8 | 1 | UniProt (P03420) | Human respiratory syncytial virus | Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1 |
| 3 | C (A) | 2-[[6-[[[2-(3-hydroxypropyl)-5-methylphenyl]amino]methyl]-2-[[3-(4-morpholinyl)propyl]amino]-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol | non-polymer | 558.7 | 1 | Chemie (TM3) | |||
| 4 | D (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 9907.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 752.9 | |
| All* | Total formula weight | 10660.3 |
