3KNE
Carbonic Anhydrase II H64C mutant in complex with an in situ formed triazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbonic anhydrase 2 | polymer | 265 | 29771.6 | 1 | UniProt (P00918) Pfam (PF00194) In PDB | Homo sapiens | Carbonic anhydrase II, CA-II, Carbonate dehydratase II, Carbonic anhydrase C, CAC |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | (4-CARBOXYPHENYL)(CHLORO)MERCURY | non-polymer | 357.2 | 1 | Chemie (BE7) | |||
| 4 | A | N-[(S)-(1-{2-oxo-2-[(3-sulfanylpropyl)amino]ethyl}-1H-1,2,3-triazol-5-yl)(phenyl)methyl]-4-sulfamoylbenzamide | non-polymer | 488.6 | 1 | Chemie (DAW) | |||
| 5 | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence modifications
A: 1 - 260 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Cys 64 | His 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29771.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 911.1 | |
| All* | Total formula weight | 30682.7 |
