3KMG
The X-ray Crystal Structure of PPAR-gamma in Complex with an Indole Derivative Modulator, GSK538, and an SRC-1 Peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | Peroxisome proliferator-activated receptor gamma | polymer | 272 | 31094.1 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma, Nuclear receptor subfamily 1 group C member 3 |
| 2 | B, D (B, E) | Steroid Receptor Coactivator-1 | polymer | 27 | 2830.2 | 2 | |||
| 3 | E, F (A, D) | 4'-[(2,3-dimethyl-5-{[(1S)-1-phenylpropyl]carbamoyl}-1H-indol-1-yl)methyl]biphenyl-2-carboxylic acid | non-polymer | 516.6 | 2 | Chemie (538) | |||
| 4 | G, H, I, J (A, B, D, E) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 67848.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1033.3 | |
| All* | Total formula weight | 68881.9 |
