3KMG

The X-ray Crystal Structure of PPAR-gamma in Complex with an Indole Derivative Modulator, GSK538, and an SRC-1 Peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Peroxisome proliferator-activated receptor gamma	polymer	272	31094.1	2	UniProt (P37231) Pfam (PF00104) In PDB	Homo sapiens (human)	PPAR-gamma, Nuclear receptor subfamily 1 group C member 3
2	B, E	Steroid Receptor Coactivator-1	polymer	27	2830.2	2
3	A, D	4'-[(2,3-dimethyl-5-{[(1S)-1-phenylpropyl]carbamoyl}-1H-indol-1-yl)methyl]biphenyl-2-carboxylic acid	non-polymer		516.6	2	Chemie (538)
4		water	water		18.0	204	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	67848.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1033.3
All*	Total formula weight	68881.9

*Water molecules are not included.