3KLV
M296I G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3D polymerase | polymer | 476 | 53498.7 | 1 | UniProt (Q9QCE3) Pfam (PF00680) | Foot-and-mouth disease virus - type C | rna dependent rna polymerase |
| 2 | B (B) | RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3') | polymer | 7 | 2236.4 | 1 | |||
| 3 | C (C) | RNA (5'-R(*GP*GP*CP*CP*C)-3') | polymer | 5 | 1561.0 | 1 | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 1 - 470 (UniProt: Q9QCE3)
| PDB | External Database | Details |
|---|---|---|
| Ser 62 | Gly 1919 | engineered mutation |
| Ile 296 | Met 2153 | engineered mutation |
| Ala 471 | - | expression tag |
| Ala 472 | - | expression tag |
| Leu 473 | - | expression tag |
| Glu 474 | - | expression tag |
| His 475 | - | expression tag |
| His 476 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 57296.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 57344.7 |
