Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3KJQ

Caspase 8 with covalent inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACaspase-8polymer16418640.11UniProt (Q14790)
Pfam (PF00656)
In PDB
Homo sapiens (human)CASP-8, ICE-like apoptotic protease 5, MORT1-associated CED-3 homolog, MACH, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, FLICE, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 subunit p18, Caspase-8 subunit p10
2BCaspase-8polymer9510901.41UniProt (Q14790)
Pfam (PF00656)
In PDB
Homo sapiens (human)CASP-8, ICE-like apoptotic protease 5, MORT1-associated CED-3 homolog, MACH, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, FLICE, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 subunit p18, Caspase-8 subunit p10
3A(3S)-3-({[(5S,8R)-2-(3-carboxypropyl)-8-(2-{[(4-chlorophenyl)acetyl]amino}ethyl)-1,3-dioxo-2,3,5,8-tetrahydro-1H-[1,2,4]triazolo[1,2-a]pyridazin-5-yl]carbonyl}amino)-4-oxopentanoic acidnon-polymer592.02Chemie (B94)
4waterwater18.0146Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29541.5
Non-Polymers*Number of molecules2
Total formula weight1184.0
All*Total formula weight30725.5
*Water molecules are not included.

222926

PDB entries from 2024-07-24

PDB statisticsPDBj update infoContact PDBjnumon