3KHV
Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Urokinase-type plasminogen activator | polymer | 253 | 28442.4 | 1 | UniProt (P00749) Pfam (PF00089) In PDB | Homo sapiens (human) | U-plasminogen activator, uPA, Urokinase-type plasminogen activator chain B |
2 | A | [4-(aminomethyl)phenyl]methanol | non-polymer | 137.2 | 1 | Chemie (4AL) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
5 | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence modifications
A: 16 - 250 (UniProt: P00749)
PDB | External Database | Details |
---|---|---|
Ala 122 | Cys 299 | engineered mutation |
Gln 145 | Asn 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28442.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 383.4 | |
All* | Total formula weight | 28825.8 |