3KFM

Crystal Structure of the GluA4 Ligand-Binding domain L651V mutant in complex with kainate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Glutamate receptor 4	polymer	257	28723.2	1	UniProt (P19493) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB	Rattus norvegicus (brown rat rat rats)	GluR-4, GluR4, GluR-D, Glutamate receptor ionotropic, AMPA 4, AMPA-selective glutamate receptor 4
2	A	3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE	non-polymer		213.2	1	Chemie (KAI)
3		water	water		18.0	175	Chemie (HOH)

Sequence modifications

A: 1 - 113 (UniProt: P19493)
A: 116 - 257 (UniProt: P19493)

PDB	External Database	Details
Gly 114	-	linker
Thr 115	-	linker
Val 134	Leu 672	engineered mutation
Arg 227	Gly 765	SEE REMARK 999
Thr 228	Asn 766	SEE REMARK 999
Pro 229	Ala 767	SEE REMARK 999
Ser 238	Asn 776	SEE REMARK 999
Ala 240	Gln 778	SEE REMARK 999
Val 242	Leu 780	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28723.2
Non-Polymers*	Number of molecules	1
	Total formula weight	213.2
All*	Total formula weight	28936.4

*Water molecules are not included.