3KFM
Crystal Structure of the GluA4 Ligand-Binding domain L651V mutant in complex with kainate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamate receptor 4 | polymer | 257 | 28723.2 | 1 | UniProt (P19493) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluR-4, GluR4, GluR-D, Glutamate receptor ionotropic, AMPA 4, AMPA-selective glutamate receptor 4 |
| 2 | B (A) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 1 | Chemie (KAI) PubChem (3816) PubChem (23616889) PubChem (10255) PubChem (73345) PubChem (45039619) PubChem (3083828) PubChem (5317452) PubChem (5318769) PubChem (6603893) PubChem (6453379) PubChem (6604705) PubChem (101994997) PubChem (10036135) PubChem (11095940) PubChem (135037246) | |||
| 3 | C (A) | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A: 1 - 113 (UniProt: P19493)
A: 116 - 257 (UniProt: P19493)
A: 116 - 257 (UniProt: P19493)
| PDB | External Database | Details |
|---|---|---|
| Gly 114 | - | linker |
| Thr 115 | - | linker |
| Val 134 | Leu 672 | engineered mutation |
| Arg 227 | Gly 765 | SEE REMARK 999 |
| Thr 228 | Asn 766 | SEE REMARK 999 |
| Pro 229 | Ala 767 | SEE REMARK 999 |
| Ser 238 | Asn 776 | SEE REMARK 999 |
| Ala 240 | Gln 778 | SEE REMARK 999 |
| Val 242 | Leu 780 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28723.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 213.2 | |
| All* | Total formula weight | 28936.4 |
