3KD0
Human thioredoxin C35S,C62S,C69S,C73S mutant showing cadmium chloride bound to the active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thioredoxin | polymer | 105 | 11686.2 | 1 | UniProt (P10599) Pfam (PF00085) | Homo sapiens (human) | Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP |
| 2 | B, C, E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 3 | D (A) | CADMIUM ION | non-polymer | 112.4 | 1 | Chemie (CD) | |||
| 4 | G (A) | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A: 1 - 105 (UniProt: P10599)
| PDB | External Database | Details |
|---|---|---|
| Ser 35 | Cys 35 | engineered mutation |
| Ser 62 | Cys 62 | engineered mutation |
| Ser 69 | Cys 69 | engineered mutation |
| Ser 73 | Cys 73 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11686.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 254.2 | |
| All* | Total formula weight | 11940.4 |
