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3KCX

Factor inhibiting HIF-1 alpha in complex with Clioquinol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hypoxia-inducible factor 1-alpha inhibitorpolymer33539153.01UniProt (Q9NWT6)
Pfam (PF13621)
Homo sapiens (human)Hypoxia-inducible factor asparagine hydroxylase, Factor inhibiting HIF-1, FIH-1
2B
(A)
FE (II) IONnon-polymer55.81Chemie (FE2)
3C, D
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
4E, F, G
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
5H
(A)
5-chloro-7-iodoquinolin-8-olnon-polymer305.51Chemie (CQL)
6I
(A)
waterwater18.068Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39153.0
Non-Polymers*Number of molecules7
Total formula weight829.8
All*Total formula weight39982.8
*Water molecules are not included.

239149

PDB entries from 2025-07-23

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