3KC0
Crystal structure of human liver FBPase in complex with tricyclic inhibitor 10b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fructose-1,6-bisphosphatase 1 | polymer | 337 | 36728.2 | 4 | UniProt (P09467) Pfam (PF00316) Pfam (PF18913) | Homo sapiens (human) | FBPase 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 |
| 2 | E, F, G, H (A, B, C, D) | [(8H-indeno[1,2-d][1,3]thiazol-4-yloxy)methyl]phosphonic acid | non-polymer | 283.2 | 4 | Chemie (2T5) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146912.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1133.0 | |
| All* | Total formula weight | 148045.9 |
