3KB8

2.09 Angstrom resolution structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-1) from Bacillus anthracis str. 'Ames Ancestor' in complex with GMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Hypoxanthine phosphoribosyltransferase	polymer	204	22975.3	4	UniProt (C3P9L0) Pfam (PF00156) UniProt (by SIFTS) (B9ZW32)	Bacillus anthracis str.
2	E, F, G (E, F, G)	beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose	branched		342.3	3	In PDB BIRD (PRD_900003)		sucrose
3	H, I, J, K, N... (A, B, C, D)	PHOSPHATE ION	non-polymer		95.0	13	Chemie (PO4)
4	L, Q (A, B)	GUANOSINE-5'-MONOPHOSPHATE	non-polymer		363.2	2	Chemie (5GP)
5	M, S (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	R (B)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7	AA, BA, CA, Z (B, C, D, A)	water	water		18.0	253	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 180 (UniProt: C3P9L0)

PDB	External Database	Details
Met -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	91901.3
Branched	Number of molecules	3
	Total formula weight	1026.9
Non-Polymers*	Number of molecules	18
	Total formula weight	2101.8
All*	Total formula weight	95029.9

*Water molecules are not included.