3K9X
X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | PROTEIN (Coagulation factor X) | polymer | 94 | 10213.3 | 2 | UniProt (P00742) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor, Factor X light chain, Factor X heavy chain, Activated factor Xa heavy chain |
| 2 | B, D (B, D) | PROTEIN (Coagulation factor X) | polymer | 238 | 26871.6 | 2 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor, Factor X light chain, Factor X heavy chain, Activated factor Xa heavy chain |
| 3 | E, F, G, K, L... (A, B, D) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 4 | H, M (B, D) | N-{N'-(2-methyl-1-benzofuran-5-yl)-N-[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]carbamimidoyl}pyridine-3-carboxamide | non-polymer | 516.6 | 2 | Chemie (MBM) | |||
| 5 | I, N (B, D) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | J, O (B, D) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 669 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 74169.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1711.9 | |
| All* | Total formula weight | 75881.8 |
