3K9B
Crystal structure of human liver carboxylesterase 1 (hCE1) in covalent complex with the nerve agent Cyclosarin (GF)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Liver carboxylesterase 1 | polymer | 529 | 58401.0 | 3 | UniProt (P23141) Pfam (PF00135) | Homo sapiens (human) | Acyl coenzyme A:cholesterol acyltransferase, ACAT, Monocyte/macrophage serine esterase, HMSE, Serine esterase 1, Brain carboxylesterase hBr1, Triacylglycerol hydrolase, TGH, Egasyn, Retinyl ester hydrolase, REH |
| 2 | D, E, F (A, B, C) | cyclohexyl (S)-methylphosphonofluoridoate | non-polymer | 180.2 | 3 | Chemie (WW2) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, B, C: 1024 - 1553 (UniProt: P23141)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 362 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 175202.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 540.5 | |
| All* | Total formula weight | 175743.3 |
