3K98
HSP90 N-terminal domain in complex with (1R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Heat shock protein HSP 90-alpha | polymer | 232 | 26411.7 | 2 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (human) | HSP 86, Renal carcinoma antigen NY-REN-38 |
2 | A, B | (1R)-2-[(5-chloro-2,4-dihydroxyphenyl)carbonyl]-N-ethyl-2,3-dihydro-1H-isoindole-1-carboxamide | non-polymer | 360.8 | 2 | Chemie (1RC) | |||
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 225 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
Met 8 | - | initiating methionine |
Leu 226 | - | expression tag |
Glu 227 | - | expression tag |
His 228 | - | expression tag |
His 229 | - | expression tag |
His 230 | - | expression tag |
His 231 | - | expression tag |
His 232 | - | expression tag |
His 233 | - | expression tag |
His 234 | - | expression tag |
His 235 | - | expression tag |
His 236 | - | expression tag |
His 237 | - | expression tag |
His 238 | - | expression tag |
His 239 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 52823.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 816.6 | |
All* | Total formula weight | 53640.0 |