3K97
HSP90 N-terminal domain in complex with 4-chloro-6-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Heat shock protein HSP 90-alpha | polymer | 251 | 28472.9 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (human) | HSP 86, Renal carcinoma antigen NY-REN-38 |
2 | A | 4-chloro-6-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol | non-polymer | 331.8 | 1 | Chemie (4CD) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
4 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A: 9 - 236 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
Met -14 | - | expression tag |
Lys -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
Asp -6 | - | expression tag |
Tyr -5 | - | expression tag |
Gly -4 | - | expression tag |
Ile -3 | - | expression tag |
Pro -2 | - | expression tag |
Thr -1 | - | expression tag |
Thr 0 | - | expression tag |
Glu 1 | - | expression tag |
Asn 2 | - | expression tag |
Leu 3 | - | expression tag |
Tyr 4 | - | expression tag |
Phe 5 | - | expression tag |
Gln 6 | - | expression tag |
Ala 7 | - | expression tag |
Leu 8 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28472.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 409.9 | |
All* | Total formula weight | 28882.8 |