3K8O
Crystal structure of human purine nucleoside phosphorylase in complex with DATMe-ImmH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E, Q, S, T, U... | Purine nucleoside phosphorylase | polymer | 289 | 32184.9 | 6 | UniProt (P00491) Pfam (PF01048) In PDB | Homo sapiens (human) | PNP, Inosine phosphorylase |
2 | Y, E, Q, S, T... | SULFATE ION | non-polymer | 96.1 | 16 | Chemie (SO4) | |||
3 | Y, E, Q, S, T... | 7-({[(1R,2S)-2,3-DIHYDROXY-1-(HYDROXYMETHYL)PROPYL]AMINO}METHYL)-3,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE | non-polymer | 268.3 | 6 | Chemie (229) | |||
4 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
E, Q, S, T, U, Y: 1 - 289 (UniProt: P00491)
PDB | External Database | Details |
---|---|---|
Ser 51 | Gly 51 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 193109.3 | |
Non-Polymers* | Number of molecules | 22 |
Total formula weight | 3146.6 | |
All* | Total formula weight | 196255.9 |