3K7V

Protein phosphatase 2A core complex bound to dinophysistoxin-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	polymer	589	65378.3	1	UniProt (P30153) Pfam (PF02985)	Homo sapiens (human)	PP2A, subunit A, PR65-alpha isoform, PP2A, subunit A, R1-alpha isoform, Medium tumor antigen-associated 61 kDa protein
2	B (C)	Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	polymer	309	35636.2	1	UniProt (P67775) Pfam (PF00149)	Homo sapiens (human)	PP2A-alpha, Replication protein C, RP-C
3	C, G, H (A, C)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	D (C)	(2R)-3-[(2S,5R,6R,8S)-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-6'-{(1S,3S)-3-[(2S,3R,6R,11R)-3,11-dimethyl-1,7-dioxaspiro[5.5]undec-2-yl]-1-hydroxybutyl}-8'-hydroxy-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]-1-methylprop-2-en-1-yl}-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoic acid	non-polymer		819.0	1	Chemie (XT1) PubChem (20055920) PubChem (22832344) PubChem (56928090) PubChem (177415069) PubChem (90477428) PubChem (104773) PubChem (101594210) PubChem (6437058) PubChem (9940710) PubChem (132477948) PubChem (146159834) PubChem (157020465) PubChem (162956458) PubChem (162956459) PubChem (125183153) PubChem (166640103) PubChem (172013198) PubChem (156588209) PubChem (162956460) PubChem (162956461)
5	E, F (C)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN) PubChem (27854)
6	I, J (A, C)	water	water		18.0	43	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	101014.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1217.1
All*	Total formula weight	102231.6

*Water molecules are not included.