3K7H
Crystal structure of the E95K mutant of the Indian Hedgehog N-terminal signalling domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Indian hedgehog protein | polymer | 187 | 21115.7 | 1 | UniProt (Q14623) Pfam (PF01085) | Homo sapiens (human) | IHH, HHG-2 |
| 2 | B (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (B) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
B: 28 - 202 (UniProt: Q14623)
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | initiating methionine |
| Arg 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| His 20 | - | expression tag |
| His 21 | - | expression tag |
| His 22 | - | expression tag |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Lys 95 | Glu 95 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21115.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 161.5 | |
| All* | Total formula weight | 21277.2 |
