3K65
Crystal Structure of Prethombin-2/Fragment-2 Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Prothrombin | polymer | 116 | 12623.6 | 1 | UniProt (P00734) Pfam (PF00051) | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain |
| 2 | B (B) | Prothrombin | polymer | 308 | 35387.4 | 1 | UniProt (P00734) Pfam (PF09396) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II, Activation peptide fragment 1, Activation peptide fragment 2, Thrombin light chain, Thrombin heavy chain |
| 3 | C, D (A) | 1,4-BUTANEDIOL | non-polymer | 90.1 | 2 | Chemie (BU1) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
B: 272 - 579 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 525 | Ser 568 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48011.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 180.2 | |
| All* | Total formula weight | 48191.2 |
