3K3A
Crystal Structure of B/Perth Neuraminidase D197E mutant in complex with Oseltamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Neuraminidase | polymer | 397 | 43838.9 | 16 | UniProt (Q3S340) | Influenza B virus (Viruses) | |
| 2 | AA, AB, DB, EA, GB... (D, L, M, E, N...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) | |||
| 3 | BA, BB, EB, FA, HB... (D, L, M, E, N...) | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) PubChem (271) | |||
| 4 | CA, CB, FB, GA, IB... (D, L, M, E, N...) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 16 | Chemie (G39) PubChem (40640967) PubChem (40640969) PubChem (40640971) PubChem (44345914) PubChem (40640973) PubChem (58753598) PubChem (71038155) PubChem (71065667) PubChem (449381) PubChem (95162772) PubChem (121452907) PubChem (4631786) PubChem (124637832) PubChem (129886749) PubChem (134694948) PubChem (137378365) | |||
| 5 | DA, MB, T, TA (E, P, A, J) | YTTRIUM (III) ION | non-polymer | 88.9 | 4 | Chemie (YT3) PubChem (168049) | |||
| 6 | AC, BC, CC, DC, EC... (K, L, M, N, O...) | water | water | 18.0 | 635 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 70 - 466 (UniProt: Q3S340)
| PDB | External Database | Details |
|---|---|---|
| Glu 197 | Asp 197 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 701421.8 | |
| Non-Polymers* | Number of molecules | 52 |
| Total formula weight | 9085.8 | |
| All* | Total formula weight | 710507.6 |
