3K3A
Crystal Structure of B/Perth Neuraminidase D197E mutant in complex with Oseltamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Neuraminidase | polymer | 397 | 43838.9 | 16 | UniProt (Q3S340) Pfam (PF00064) | Influenza B virus (Viruses) | |
| 2 | AA, AB, DB, EA, GB... (D, L, M, E, N...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 16 | Chemie (NAG) | |||
| 3 | BA, BB, EB, FA, HB... (D, L, M, E, N...) | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) | |||
| 4 | CA, CB, FB, GA, IB... (D, L, M, E, N...) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 16 | Chemie (G39) | |||
| 5 | DA, MB, T, TA (E, P, A, J) | YTTRIUM (III) ION | non-polymer | 88.9 | 4 | Chemie (YT3) | |||
| 6 | AC, BC, CC, DC, EC... (K, L, M, N, O...) | water | water | 18.0 | 635 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 70 - 466 (UniProt: Q3S340)
| PDB | External Database | Details |
|---|---|---|
| Glu 197 | Asp 197 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 701421.8 | |
| Non-Polymers* | Number of molecules | 52 |
| Total formula weight | 9085.8 | |
| All* | Total formula weight | 710507.6 |
