3K1R

Structure of harmonin NPDZ1 in complex with the SAM-PBM of Sans

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Harmonin	polymer	192	21964.3	1	UniProt (Q9Y6N9) Pfam (PF21219) Pfam (PF00595) In PDB	Homo sapiens (human)	Harmonin scaffold protein, Usher syndrome type-1C protein, Autoimmune enteropathy-related antigen AIE-75, Antigen NY-CO-38/NY-CO-37, PDZ-73 protein, Renal carcinoma antigen NY-REN-3
2	B	Usher syndrome type-1G protein	polymer	74	8414.7	1	UniProt (Q495M9) Pfam (PF00536) In PDB	Homo sapiens (human)	Sans scaffold protein, Scaffold protein containing ankyrin repeats and SAM domain
3		water	water		18.0	239	Chemie (HOH)

Sequence modifications

A: 1 - 192 (UniProt: Q9Y6N9)

PDB	External Database	Details
Glu 157	Lys 157	engineered mutation

B: 388 - 461 (UniProt: Q495M9)

PDB	External Database	Details
Glu 437	Lys 437	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30379.0
All*	Total formula weight	30379.0

*Water molecules are not included.