3JZB
Crystal Structure of TR-alfa bound to the selective thyromimetic TRIAC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THRA protein | polymer | 267 | 30777.9 | 1 | UniProt (Q6FH41) Pfam (PF00104) UniProt (by SIFTS) (P10827) | Homo sapiens (human) | Thyroid hormone receptor, alpha |
| 2 | B (A) | [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID | non-polymer | 621.9 | 1 | Chemie (4HY) | |||
| 3 | C (A) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A: 148 - 410 (UniProt: Q6FH41)
| PDB | External Database | Details |
|---|---|---|
| Gly 144 | - | expression tag |
| Ser 145 | - | expression tag |
| His 146 | - | expression tag |
| Met 147 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30777.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 621.9 | |
| All* | Total formula weight | 31399.9 |
