3JWD
Structure of HIV-1 gp120 with gp41-Interactive Region: Layered Architecture and Basis of Conformational Mobility
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, B) | HIV-1 GP120 ENVELOPE GLYCOPROTEIN | polymer | 379 | 42117.6 | 2 | Human immunodeficiency virus 1 | ||
| 2 | B, F (C, D) | T-cell surface glycoprotein CD4 | polymer | 184 | 20419.3 | 2 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) | Homo sapiens (human) | T-cell surface antigen T4/Leu-3 |
| 3 | C, G (L, O) | FAB 48D LIGHT CHAIN | polymer | 213 | 23252.8 | 2 | Homo sapiens (human) | ||
| 4 | D, H (H, P) | FAB 48D HEAVY CHAIN | polymer | 220 | 23515.3 | 2 | Homo sapiens (human) | ||
| 5 | AA, BA, I, J, K... (B, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 19 | Chemie (NAG) | |||
| 6 | CA, Z (P, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | DA, EA, FA, GA, HA... (A, C, L, H, B...) | water | water | 18.0 | 450 | Chemie (HOH) |
Sequence modifications
C, D: 1001 - 1183 (UniProt: P01730)
| PDB | External Database | Details |
|---|---|---|
| Met 1000 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 218609.9 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4387.1 | |
| All* | Total formula weight | 222997.1 |
