3JW0
E2~Ubiquitin-HECT
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ubiquitin-conjugating enzyme E2 D2 | polymer | 146 | 16610.0 | 2 | UniProt (P62837) Pfam (PF00179) In PDB | Homo sapiens (human) | Ubiquitin-protein ligase D2, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2-17 kDa 2, E2(17)KB 2 |
2 | C, D | E3 ubiquitin-protein ligase NEDD4-like | polymer | 385 | 45451.6 | 2 | UniProt (Q96PU5) Pfam (PF00632) In PDB | Homo sapiens (human) | Nedd4-2, NEDD4.2 |
3 | X, Y | Ubiquitin | polymer | 81 | 8922.1 | 2 | UniProt (P62988) Pfam (PF00240) UniProt (by SIFTS) (P0CG48) In PDB | Homo sapiens (human) | |
4 | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 147 (UniProt: P62837)
C, D: 576 - 955 (UniProt: Q96PU5)
X, Y: 1 - 76 (UniProt: P62988)
PDB | External Database | Details |
---|---|---|
Ser 3 | Leu 3 | engineered mutation |
Ser 85 | Cys 85 | engineered mutation |
Lys 98 | Thr 98 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 571 | - | expression tag |
Ser 572 | - | expression tag |
Pro 573 | - | expression tag |
Glu 574 | - | expression tag |
Phe 575 | - | expression tag |
Ser 922 | Cys 347 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
Gly -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 141967.5 | |
All* | Total formula weight | 141967.5 |