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3JVK

Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Bromodomain-containing protein 4polymer13115385.71UniProt (Q9ESU6)
Pfam (PF00439)
Mus musculus (mouse)Mitotic chromosome-associated protein, MCAP
2B
(C)
histone H3.3 peptidepolymer8885.01UniProt (P84243)
3C
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4D, E
(A, C)
waterwater18.0104Chemie (HOH)
Sequence modifications
A: 42 - 168 (UniProt: Q9ESU6)
PDBExternal DatabaseDetails
Gly 38-expression tag
Ala 39-expression tag
Met 40-expression tag
Gly 41-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight16270.7
Non-Polymers*Number of molecules1
Total formula weight62.1
All*Total formula weight16332.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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