3JUV
Crystal structure of human lanosterol 14alpha-demethylase (CYP51)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lanosterol 14-alpha demethylase | polymer | 461 | 52769.5 | 1 | UniProt (Q16850) Pfam (PF00067) | Homo sapiens (human) | LDM, Cytochrome P450 51A1, CYPLI, P450LI, Sterol 14-alpha demethylase, P450-14DM, P45014DM |
| 2 | B (B) | Cycloheptakis-(1-4)-(alpha-D-glucopyranose) | branched | 1153.0 | 1 | In PDB BIRD (PRD_900012) GlyTouCan (G01435GL) | beta-cyclodextrin | ||
| 3 | C (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 4 | D (A) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 54 - 502 (UniProt: Q16850)
| PDB | External Database | Details |
|---|---|---|
| Met 49 | - | expression tag |
| Ala 50 | - | expression tag |
| Lys 51 | - | expression tag |
| Lys 52 | - | expression tag |
| Thr 53 | - | expression tag |
| Thr 503 | - | expression tag |
| His 504 | - | expression tag |
| His 505 | - | expression tag |
| His 506 | - | expression tag |
| His 507 | - | expression tag |
| His 508 | - | expression tag |
| His 509 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52769.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1153.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 616.5 | |
| All* | Total formula weight | 54539.0 |
