3JUI

Crystal Structure of the C-terminal Domain of Human Translation Initiation Factor eIF2B epsilon Subunit

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Translation initiation factor eIF-2B subunit epsilon	polymer	182	21384.5	1	UniProt (Q13144) Pfam (PF02020)	Homo sapiens (human)	eIF-2B GDP-GTP exchange factor subunit epsilon
2	B (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	C (A)	water	water		18.0	94	Chemie (HOH)

Sequence modifications

A: 548 - 721 (UniProt: Q13144)

PDB	External Database	Details
Gly 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
Mse 547	-	expression tag
Gly 678	Glu 678	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	21384.5
Non-Polymers*	Number of molecules	1
	Total formula weight	92.1
All*	Total formula weight	21476.6

*Water molecules are not included.