3JSX
X-ray Crystal structure of NAD(P)H: Quinone Oxidoreductase-1 (NQO1) bound to the coumarin-based inhibitor AS1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | NAD(P)H dehydrogenase [quinone] 1 | polymer | 273 | 30776.4 | 8 | UniProt (P15559) Pfam (PF02525) | Homo sapiens (human) | Quinone reductase 1, NAD(P)H:quinone oxidoreductase 1, QR1, DT-diaphorase, DTD, Azoreductase, Phylloquinone reductase, Menadione reductase |
| 2 | I, K, M, O, Q... (A, B, C, D, E...) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 8 | Chemie (FAD) | |||
| 3 | J, L, N, P, R... (A, B, C, D, E...) | 4-hydroxy-6,7-dimethyl-3-(naphthalen-1-ylmethyl)-2H-chromen-2-one | non-polymer | 330.4 | 8 | Chemie (CC2) | |||
| 4 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 434 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 246211.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 8927.4 | |
| All* | Total formula weight | 255138.7 |
