3JQ5
Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phospholipase A2 isoform 3 | polymer | 119 | 13128.5 | 1 | UniProt (P60045) Pfam (PF00068) In PDB | Naja sagittifera (Andaman cobra) | Phosphatidylcholine 2-acylhydrolase |
| 2 | B | Amyloid Beta Peptide | polymer | 8 | 978.0 | 1 | UniProt (by SIFTS) (P05067) In PDB | ||
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | water | water | 18.0 | 99 | Chemie (HOH) |
Sequence modifications
A: 1 - 120 (UniProt: P60045)
| PDB | External Database | Details |
|---|---|---|
| Ala 20 | Gln 26 | SEE REMARK 999 |
| Thr 47 | Val 53 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14106.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 14146.6 |
