3JPV
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a pyrrolo[2,3-a]carbazole ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Proto-oncogene serine/threonine-protein kinase Pim-1 | polymer | 313 | 35590.5 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (human) | |
2 | B | Peptide (PIMTIDE) ARKRRRHPSGPPTA | polymer | 14 | 1592.8 | 1 | |||
3 | A | 1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde | non-polymer | 234.3 | 1 | Chemie (1DR) | |||
4 | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence modifications
A: 1 - 312 (UniProt: P11309)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
Gly 250 | Arg 341 | see REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 37183.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 234.3 | |
All* | Total formula weight | 37417.6 |