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3JPT

Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-fluoro chloro methylene triphosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (human)
2B
(D)
5'-D(P*GP*TP*CP*GP*G)-3'polymer51536.01
3C
(P)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3'polymer103045.01
4D
(T)
5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'polymer164829.11
5E
(A)
5'-O-[(S)-{[(S)-[(S)-chloro(fluoro)phosphonomethyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxyguanosinenon-polymer557.61Chemie (GFC)
6F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7G, H, I
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
8J, K, L
(A)
CHLORIDE IONnon-polymer35.53Chemie (CL)
9M, N, O, P
(A, D, P, T)
waterwater18.0384Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47651.8
Non-Polymers*Number of molecules8
Total formula weight757.3
All*Total formula weight48409.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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