3JCS
2.8 Angstrom cryo-EM structure of the large ribosomal subunit from the eukaryotic parasite Leishmania
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | 26S alpha ribosomal RNA | polymer | 1782 | 576874.1 | 1 | Leishmania donovani | ||
| 2 | B (2) | 26S delta ribosomal RNA | polymer | 1527 | 492600.6 | 1 | Leishmania donovani | ||
| 3 | C (3) | 26S gamma ribosomal RNA | polymer | 213 | 68191.1 | 1 | Leishmania donovani | ||
| 4 | D (4) | 26S delta ribosomal RNA | polymer | 183 | 59130.1 | 1 | Leishmania donovani | ||
| 5 | E (5) | 26S epsilon ribosomal RNA | polymer | 133 | 42869.4 | 1 | Leishmania donovani | ||
| 6 | F (6) | 26S zeta ribosomal RNA | polymer | 76 | 24254.5 | 1 | Leishmania donovani | ||
| 7 | G (7) | 5.8S ribosomal RNA | polymer | 171 | 54961.5 | 1 | Leishmania donovani | ||
| 8 | H (8) | 5S ribosomal RNA | polymer | 121 | 38840.0 | 1 | Leishmania donovani | ||
| 9 | I (A) | ribosomal protein L2 | polymer | 260 | 28331.9 | 1 | Leishmania donovani | ||
| 10 | J (B) | ribosomal protein L3 | polymer | 419 | 47672.8 | 1 | Leishmania donovani | ||
| 11 | K (C) | ribosomal protein L4 | polymer | 373 | 41228.0 | 1 | UniProt (E9BKR3) Pfam (PF00573) Pfam (PF14374) UniProt (by SIFTS) (A0A3S5H7L0) | Leishmania donovani | |
| 12 | L (D) | ribosomal protein L5 | polymer | 188 | 21710.5 | 1 | UniProt (E9BFL1) Pfam (PF00281) Pfam (PF00673) UniProt (by SIFTS) (A0A3S5H5A8) | Leishmania donovani | |
| 13 | M (E) | ribosomal protein L6 | polymer | 190 | 21567.3 | 1 | UniProt (E9BFB5) Pfam (PF00347) UniProt (by SIFTS) (A0A3S7WWL2) | Leishmania donovani | |
| 14 | N (F) | ribosomal protein L6e | polymer | 195 | 21208.9 | 1 | Leishmania donovani | ||
| 15 | O (G) | ribosomal protein L8e | polymer | 348 | 39175.2 | 1 | UniProt (E9B949) Pfam (PF01248) | Leishmania donovani | |
| 16 | P (H) | ribosomal protein L13 | polymer | 222 | 25477.2 | 1 | Leishmania donovani | ||
| 17 | Q (I) | ribosomal protein L13e | polymer | 220 | 24803.0 | 1 | Leishmania donovani | ||
| 18 | R (J) | ribosomal protein L14 | polymer | 139 | 14982.6 | 1 | UniProt (E9BSQ4) Pfam (PF00238) UniProt (by SIFTS) (A0A3Q8IIA7) | Leishmania donovani | |
| 19 | S (K) | ribosomal protein L14e | polymer | 233 | 26054.8 | 1 | UniProt (E9BG02) Pfam (PF01929) Pfam (PF00467) | Leishmania donovani | |
| 20 | T (L) | ribosomal protein L15 | polymer | 145 | 16165.9 | 1 | UniProt (E9BSQ2) Pfam (PF00828) UniProt (by SIFTS) (A0A3Q8IGI9) | Leishmania donovani | |
| 21 | U (M) | ribosomal protein L15e | polymer | 204 | 24498.0 | 1 | UniProt (E9BMB4) Pfam (PF00827) | Leishmania donovani | |
| 22 | V (N) | ribosomal protein L16 | polymer | 213 | 24607.2 | 1 | UniProt (E9B840) Pfam (PF00252) UniProt (by SIFTS) (A0A3S5H5C4) | Leishmania donovani | |
| 23 | W (O) | ribosomal protein L18 | polymer | 305 | 34100.6 | 1 | UniProt (E9BS61) Pfam (PF17144) Pfam (PF14204) UniProt (by SIFTS) (A0A3Q8IJC5) | Leishmania donovani | |
| 24 | X (P) | ribosomal protein L18e | polymer | 198 | 22071.1 | 1 | UniProt (E9BUI1) Pfam (PF17135) UniProt (by SIFTS) (A0A3S7XBN1) | Leishmania donovani | |
| 25 | Y (Q) | ribosomal protein L19e | polymer | 245 | 28142.2 | 1 | UniProt (E9B8Q2) Pfam (PF01280) | Leishmania donovani | |
| 26 | Z (R) | ribosomal protein L20e | polymer | 179 | 20834.4 | 1 | UniProt (E9BRT7) Pfam (PF01775) UniProt (by SIFTS) (A0A3Q8II03) | Leishmania donovani | |
| 27 | AA (S) | ribosomal protein L21e | polymer | 159 | 18059.3 | 1 | UniProt (E9BRE2) Pfam (PF01157) UniProt (by SIFTS) (A0A3Q8ICH0) | Leishmania donovani | |
| 28 | BA (T) | ribosomal protein L22 | polymer | 166 | 19154.6 | 1 | UniProt (E9BGL6) Pfam (PF00237) UniProt (by SIFTS) (A0A3S7WY02) | Leishmania donovani | |
| 29 | CA (U) | ribosomal protein L22e | polymer | 129 | 15030.5 | 1 | UniProt (E9BU52) Pfam (PF01776) UniProt (by SIFTS) (A0A3Q8IJA8) | Leishmania donovani | |
| 30 | DA (V) | ribosomal protein L23 | polymer | 145 | 16389.5 | 1 | UniProt (E9B8R9) Pfam (PF00276) | Leishmania donovani | |
| 31 | EA (W) | ribosomal protein L24 | polymer | 143 | 16217.1 | 1 | Leishmania donovani | ||
| 32 | FA (X) | ribosomal protein L24e | polymer | 124 | 14622.2 | 1 | Leishmania donovani | ||
| 33 | GA (Y) | ribosomal protein L27e | polymer | 134 | 15455.3 | 1 | UniProt (E9BP34) Pfam (PF00467) Pfam (PF01777) | Leishmania donovani | |
| 34 | HA (Z) | ribosomal protein L28e | polymer | 147 | 16409.0 | 1 | UniProt (E9BAU9) Pfam (PF01778) UniProt (by SIFTS) (A0A3Q8I959) | Leishmania donovani | |
| 35 | IA (a) | ribosomal protein L29 | polymer | 127 | 15232.2 | 1 | UniProt (E9BIP6) Pfam (PF00831) | Leishmania donovani | |
| 36 | JA (b) | ribosomal protein L29e | polymer | 70 | 8033.4 | 1 | UniProt (E9BU64) Pfam (PF01779) | Leishmania donovani | |
| 37 | KA (c) | ribosomal protein L30 | polymer | 252 | 28929.0 | 1 | UniProt (E9BI29) Pfam (PF08079) Pfam (PF00327) | Leishmania donovani | |
| 38 | LA (d) | ribosomal protein L30e | polymer | 104 | 11400.3 | 1 | UniProt (E9BRQ6) Pfam (PF01248) UniProt (by SIFTS) (A0A3Q8IET6) | Leishmania donovani | |
| 39 | MA (e) | ribosomal protein L31e | polymer | 183 | 20886.7 | 1 | UniProt (E9BSK4) Pfam (PF01198) | Leishmania donovani | |
| 40 | NA (f) | ribosomal protein L32e | polymer | 133 | 15403.1 | 1 | UniProt (E9BFJ5) Pfam (PF01655) UniProt (by SIFTS) (A0A3Q8IBA2) | Leishmania donovani | |
| 41 | OA (g) | ribosomal protein L33e | polymer | 144 | 16492.3 | 1 | UniProt (E9BR22) Pfam (PF01247) UniProt (by SIFTS) (A0A3Q8II82) | Leishmania donovani | |
| 42 | PA (h) | ribosomal protein L34e | polymer | 168 | 19307.1 | 1 | UniProt (E9BUA1) Pfam (PF01199) UniProt (by SIFTS) (A0A3Q8IHK2) | Leishmania donovani | |
| 43 | QA (i) | ribosomal protein L36e | polymer | 105 | 12005.2 | 1 | UniProt (E9BF65) Pfam (PF01158) UniProt (by SIFTS) (A0A3Q8IDW6) | Leishmania donovani | |
| 44 | RA (j) | ribosomal protein L37e | polymer | 83 | 9862.6 | 1 | UniProt (E9BQD7) Pfam (PF01907) UniProt (by SIFTS) (P62885) | Leishmania donovani | |
| 45 | SA (k) | ribosomal protein L38e | polymer | 83 | 9479.3 | 1 | UniProt (E9B7P2) Pfam (PF01781) | Leishmania donovani | |
| 46 | TA (l) | ribosomal protein L39e | polymer | 51 | 6504.8 | 1 | UniProt (E9BCX6) Pfam (PF00832) | Leishmania donovani | |
| 47 | UA (m) | ribosomal protein L43e | polymer | 92 | 10337.2 | 1 | UniProt (E9BFK4) Pfam (PF01780) | Leishmania donovani | |
| 48 | VA (n) | ribosomal protein L44e | polymer | 106 | 12302.7 | 1 | UniProt (E9BBL5) Pfam (PF00935) | Leishmania donovani | |
| 49 | AB, AC, AD, AE, AF... (1, 2, 5, j, 7...) | MAGNESIUM ION | non-polymer | 24.3 | 109 | Chemie (MG) | |||
| 50 | BF, CF, DF, EF, FF... (1, 2, 4, 5, 7...) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
R: 1 - 179 (UniProt: E9BRT7)
c: 1 - 252 (UniProt: E9BI29)
f: 1 - 133 (UniProt: E9BFJ5)
| PDB | External Database | Details |
|---|---|---|
| Ile 158 | Leu 158 | VARIANT |
| PDB | External Database | Details |
|---|---|---|
| Ala 49 | Gly 49 | VARIANT |
| PDB | External Database | Details |
|---|---|---|
| Lys 105 | Thr 105 | VARIANT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 48 |
| Total formula weight | 2167866.1 | |
| Non-Polymers* | Number of molecules | 109 |
| Total formula weight | 2649.2 | |
| All* | Total formula weight | 2170515.3 |
