3JBX

Cryo-electron microscopy structure of RAG Signal End Complex (C2 symmetry)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	V(D)J recombination-activating protein 1	polymer	764	87684.1	2	UniProt (O13033) Pfam (PF00097) Pfam (PF12940) In PDB	Danio rerio (zebra fish)	RAG-1, Endonuclease RAG1, E3 ubiquitin-protein ligase RAG1
2	B, D	V(D)J recombination-activating protein 2	polymer	533	59435.9	2	UniProt (Q1RLW7) Pfam (PF03089) Pfam (PF13341) UniProt (by SIFTS) (O13034) In PDB	Danio rerio (zebra fish)	RAG-2
3	E, H	5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3'	polymer	15	4563.0	2		Homo sapiens
4	F, G	5'-D(P*GP*TP*CP*TP*GP*TP*AP*GP*CP*AP*CP*TP*GP*TP*G)-3'	polymer	15	4616.0	2		Homo sapiens
5	I, K	5'-D(*GP*CP*GP*AP*TP*GP*GP*TP*TP*AP*AP*CP*CP*A)-3'	polymer	14	4304.8	2		Homo sapiens
6	J, L	5'-D(P*TP*GP*GP*TP*TP*AP*AP*CP*CP*AP*TP*CP*GP*C)-3'	polymer	14	4255.8	2		Homo sapiens
7	A, C	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
8	A, C	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)

Sequence modifications

A, C: 271 - 1031 (UniProt: O13033)

PDB	External Database	Details
Gly 268	-	expression tag
Gly 269	-	expression tag
Ser 270	-	expression tag

B, D: 1 - 530 (UniProt: Q1RLW7)

PDB	External Database	Details
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	329719.3
Non-Polymers*	Number of molecules	6
	Total formula weight	228.0
All*	Total formula weight	329947.3

*Water molecules are not included.