3JBN

Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P-tRNA

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	18S ribosomal RNA	polymer	1608	517983.4	1		Plasmodium falciparum 3D7
2	7	P-tRNA	polymer	76	24496.6	1		Escherichia coli
3	D	40S ribosomal protein uS3	polymer	209	23420.5	1	UniProt (Q8IKH8) Pfam (PF07650) Pfam (PF00189) In PDB	Plasmodium falciparum 3D7
4	E	40S ribosomal protein uS4	polymer	185	21711.6	1	UniProt (Q8I3R0) Pfam (PF00163) Pfam (PF01479) In PDB	Plasmodium falciparum 3D7
5	G	40S ribosomal protein uS5	polymer	224	24995.2	1	UniProt (Q8IL02) Pfam (PF00333) Pfam (PF03719) In PDB	Plasmodium falciparum 3D7
6	I	40S ribosomal protein uS7	polymer	189	21263.8	1	UniProt (Q8IBN5) Pfam (PF00177) In PDB	Plasmodium falciparum 3D7
7	K	40S ribosomal protein uS8	polymer	129	14769.5	1	UniProt (O77395) Pfam (PF00410) In PDB	Plasmodium falciparum 3D7
8	M	40S ribosomal protein uS9	polymer	138	15599.3	1	UniProt (Q8IAX5) Pfam (PF00380) In PDB	Plasmodium falciparum 3D7
9	W	40S ribosomal protein eS17	polymer	108	12665.0	1	UniProt (Q8I502) Pfam (PF00833) In PDB	Plasmodium falciparum 3D7
10	R	40S ribosomal protein eS12	polymer	114	12505.4	1	UniProt (O97249) Pfam (PF01248) In PDB	Plasmodium falciparum 3D7
11	O	40S ribosomal protein eS10	polymer	79	9714.3	1	UniProt (Q8IBQ5) Pfam (PF03501) In PDB	Plasmodium falciparum 3D7
12	Y	40S ribosomal protein eS19	polymer	154	17935.9	1	UniProt (Q8IFP2) Pfam (PF01090) In PDB	Plasmodium falciparum 3D7
13	Z	40S ribosomal protein eS21	polymer	72	7966.1	1	UniProt (Q8IHS5) Pfam (PF01249) In PDB	Plasmodium falciparum 3D7
14	1	40S ribosomal protein eS24	polymer	120	14008.7	1	UniProt (Q8I3R6) Pfam (PF01282) In PDB	Plasmodium falciparum 3D7
15	2	40S ribosomal protein eS25	polymer	68	7645.1	1	UniProt (Q8ILN8) Pfam (PF03297) In PDB	Plasmodium falciparum 3D7
16	3	40S ribosomal protein eS26	polymer	95	11201.1	1	UniProt (O96258) Pfam (PF01283) In PDB	Plasmodium falciparum 3D7
17	4	40S ribosomal protein eS27	polymer	76	8469.0	1	UniProt (Q8IEN2) Pfam (PF01667) In PDB	Plasmodium falciparum 3D7
18	5	40S ribosomal protein eS28	polymer	65	7220.4	1	UniProt (Q8IKL9) Pfam (PF01200) In PDB	Plasmodium falciparum 3D7
19	6	40S ribosomal protein eS30	polymer	43	4925.8	1	UniProt (O96269) Pfam (PF04758) In PDB	Plasmodium falciparum 3D7
20	B	40S ribosomal protein eS1	polymer	210	24524.2	1	UniProt (O97313) Pfam (PF01015) In PDB	Plasmodium falciparum 3D7
21	F	40S ribosomal protein eS4	polymer	257	29357.8	1	UniProt (Q8IIU8) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) In PDB	Plasmodium falciparum 3D7
22	H	40S ribosomal protein eS6	polymer	214	24612.3	1	UniProt (Q8IDR9) Pfam (PF01092) In PDB	Plasmodium falciparum 3D7
23	J	40S ribosomal protein eS7	polymer	188	21805.0	1	UniProt (Q8IET7) Pfam (PF01251) In PDB	Plasmodium falciparum 3D7
24	L	40S ribosomal protein eS8	polymer	214	24717.5	1	UniProt (Q8IM10) Pfam (PF01201) In PDB	Plasmodium falciparum 3D7
25	N	40S ribosomal protein uS10	polymer	98	11066.9	1	UniProt (Q8IK02) Pfam (PF00338) In PDB	Plasmodium falciparum 3D7
26	P	40S ribosomal protein uS11	polymer	127	13610.7	1	UniProt (Q8I3U6) In PDB	Plasmodium falciparum 3D7
27	Q	40S ribosomal protein uS12	polymer	144	16035.8	1	UniProt (O97248) Pfam (PF00164) In PDB	Plasmodium falciparum 3D7
28	S	40S ribosomal protein uS13	polymer	128	14920.5	1	UniProt (Q8IIA2) Pfam (PF00416) In PDB	Plasmodium falciparum 3D7
29	T	40S ribosomal protein uS14	polymer	48	5798.9	1	UniProt (C0H4K8) Pfam (PF00253) In PDB	Plasmodium falciparum 3D7
30	U	40S ribosomal protein uS15	polymer	149	17098.2	1	UniProt (Q8IDB0) Pfam (PF08069) Pfam (PF00312) In PDB	Plasmodium falciparum 3D7
31	V	40S ribosomal protein uS17	polymer	156	18283.5	1	UniProt (O77381) Pfam (PF16205) Pfam (PF00366) In PDB	Plasmodium falciparum 3D7
32	X	40S ribosomal protein uS19	polymer	103	11924.1	1	UniProt (C0H5C2) Pfam (PF00203) In PDB	Plasmodium falciparum 3D7
33	C	40S ribosomal protein uS2	polymer	195	21925.7	1	UniProt (Q8IJD4) Pfam (PF00318) In PDB	Plasmodium falciparum 3D7
34	AA	28S ribosomal RNA	polymer	3193	1027642.3	1		Plasmodium falciparum 3D7
35	AC	5.8S ribosomal RNA	polymer	151	48657.0	1		Plasmodium falciparum 3D7
36	AB	5S ribosomal RNA	polymer	118	38104.7	1		Plasmodium falciparum 3D7
37	AL	60S ribosomal protein eL13	polymer	211	24964.6	1	UniProt (Q8IAX6) Pfam (PF01294) In PDB	Plasmodium falciparum 3D7
38	A1	60S ribosomal protein eL27	polymer	145	16654.0	1	UniProt (Q8IKM5) Pfam (PF01777) In PDB	Plasmodium falciparum 3D7
39	A2	60S ribosomal protein eL28	polymer	118	13377.6	1	UniProt (Q8IHU0) Pfam (PF01778) In PDB	Plasmodium falciparum 3D7
40	A4	60S ribosomal protein eL29	polymer	66	7910.4	1	UniProt (C6S3J6) Pfam (PF01779) In PDB	Plasmodium falciparum 3D7
41	A6	60S ribosomal protein eL30	polymer	98	10644.4	1	UniProt (Q8IJK8) Pfam (PF01248) In PDB	Plasmodium falciparum 3D7
42	A7	60S ribosomal protein eL31	polymer	102	12051.4	1	UniProt (Q8I463) Pfam (PF01198) In PDB	Plasmodium falciparum 3D7
43	AN	60S ribosomal protein eL14	polymer	146	17139.6	1	UniProt (Q8ILE8) Pfam (PF01929) In PDB	Plasmodium falciparum 3D7
44	A8	60S ribosomal protein eL32	polymer	125	14817.9	1	UniProt (Q8I3B0) Pfam (PF01655) In PDB	Plasmodium falciparum 3D7
45	A9	60S ribosomal protein eL33	polymer	103	11982.1	1	UniProt (Q8IHT9) Pfam (PF01247) In PDB	Plasmodium falciparum 3D7
46	Aa	60S ribosomal protein eL34	polymer	106	12291.6	1	UniProt (Q8IBY4) Pfam (PF01199) In PDB	Plasmodium falciparum 3D7
47	Ab	60S ribosomal protein eL36	polymer	105	12026.5	1	UniProt (Q8I713) Pfam (PF01158) In PDB	Plasmodium falciparum 3D7
48	Ad	60S ribosomal protein eL38	polymer	76	9080.1	1	UniProt (Q8II62) Pfam (PF01781) In PDB	Plasmodium falciparum 3D7
49	Ae	60S ribosomal protein eL39	polymer	50	6409.7	1	UniProt (C0H4H3) Pfam (PF00832) In PDB	Plasmodium falciparum 3D7
50	Af	60S ribosomal protein eL40	polymer	51	5971.2	1	UniProt (Q8ID50) Pfam (PF01020) In PDB	Plasmodium falciparum 3D7
51	AP	60S ribosomal protein eL15	polymer	204	24066.5	1	UniProt (C0H4A6) Pfam (PF00827) In PDB	Plasmodium falciparum 3D7
52	Ah	60S ribosomal protein eL43	polymer	85	9477.5	1	UniProt (O96184) Pfam (PF01780) In PDB	Plasmodium falciparum 3D7
53	Ai	60S ribosomal protein eL44	polymer	95	11228.7	1	UniProt (O97231) Pfam (PF00935) In PDB	Plasmodium falciparum 3D7
54	AI	60S ribosomal protein eL6	polymer	213	24696.7	1	UniProt (Q8IDV1) In PDB	Plasmodium falciparum 3D7
55	AJ	60S ribosomal protein eL8	polymer	244	28384.1	1	UniProt (Q8ILL2) Pfam (PF01248) In PDB	Plasmodium falciparum 3D7
56	Ac	60S ribosomal protein eL37	polymer	89	10155.1	1	UniProt (C0H4L5) Pfam (PF01907) In PDB	Plasmodium falciparum 3D7
57	AK	60S ribosomal protein uL13	polymer	201	23642.2	1	UniProt (Q8IJZ7) Pfam (PF00572) In PDB	Plasmodium falciparum 3D7
58	AM	60S ribosomal protein uL14	polymer	132	14255.8	1	UniProt (Q8IE09) Pfam (PF00238) In PDB	Plasmodium falciparum 3D7
59	AS	60S ribosomal protein eL18	polymer	186	21377.6	1	UniProt (C0H5G3) Pfam (PF17135) In PDB	Plasmodium falciparum 3D7
60	AO	60S ribosomal protein uL15	polymer	147	16634.6	1	UniProt (C6KT23) Pfam (PF00828) In PDB	Plasmodium falciparum 3D7
61	AQ	60S ribosomal protein uL16	polymer	205	23612.6	1	UniProt (Q8ILV2) Pfam (PF00252) In PDB	Plasmodium falciparum 3D7
62	AR	60S ribosomal protein uL18	polymer	289	33473.6	1	UniProt (Q8ILL3) Pfam (PF17144) Pfam (PF14204) In PDB	Plasmodium falciparum 3D7
63	AW	60S ribosomal protein uL22	polymer	170	19071.5	1	UniProt (Q8IDI5) Pfam (PF00237) In PDB	Plasmodium falciparum 3D7
64	AY	60S ribosomal protein uL23	polymer	101	11431.5	1	UniProt (Q8IE82) Pfam (PF00276) In PDB	Plasmodium falciparum 3D7
65	AT	60S ribosomal protein eL19	polymer	181	21509.9	1	UniProt (C6KSY6) Pfam (PF01280) In PDB	Plasmodium falciparum 3D7
66	AZ	60S ribosomal protein uL24	polymer	121	14281.0	1	UniProt (O77364) Pfam (PF16906) Pfam (PF00467) In PDB	Plasmodium falciparum 3D7
67	A3	60S ribosomal protein uL29	polymer	119	14173.1	1	UniProt (Q8IIB4) Pfam (PF00831) In PDB	Plasmodium falciparum 3D7
68	A5	60S ribosomal protein uL30	polymer	223	26650.7	1	UniProt (O97250) Pfam (PF08079) Pfam (PF00327) In PDB	Plasmodium falciparum 3D7
69	AD	60S ribosomal protein uL2	polymer	247	26630.3	1	UniProt (Q8I3T9) Pfam (PF00181) Pfam (PF03947) In PDB	Plasmodium falciparum 3D7
70	AE	60S ribosomal protein uL3	polymer	380	43629.3	1	UniProt (Q8IJC6) Pfam (PF00297) In PDB	Plasmodium falciparum 3D7
71	AF	60S ribosomal protein uL4	polymer	390	44081.1	1	UniProt (Q8I431) Pfam (PF00573) Pfam (PF14374) In PDB	Plasmodium falciparum 3D7
72	AG	60S ribosomal protein uL5	polymer	159	18605.8	1	UniProt (Q8IBQ6) Pfam (PF00281) Pfam (PF00673) In PDB	Plasmodium falciparum 3D7
73	AU	60S ribosomal protein eL20	polymer	180	21304.9	1	UniProt (Q8IDS6) Pfam (PF01775) In PDB	Plasmodium falciparum 3D7
74	AH	60S ribosomal protein uL6	polymer	185	21004.9	1	UniProt (Q8IE85) Pfam (PF00347) In PDB	Plasmodium falciparum 3D7
75	AV	60S ribosomal protein eL21	polymer	155	18173.5	1	UniProt (Q8ILK3) Pfam (PF01157) In PDB	Plasmodium falciparum 3D7
76	Ag	60S ribosomal protein eL41	polymer	37	4906.0	1	UniProt (C6S3G4) Pfam (PF05162) In PDB	Plasmodium falciparum 3D7
77	AX	60S ribosomal protein eL22	polymer	97	11680.9	1	UniProt (Q8IB51) Pfam (PF01776) In PDB	Plasmodium falciparum 3D7
78	A0	60S ribosomal protein eL24	polymer	62	7383.6	1	UniProt (Q8IEM3) Pfam (PF01246) In PDB	Plasmodium falciparum 3D7

Sequence modifications

H: 1 - 213 (UniProt: Q8IDR9)

PDB	External Database	Details
Ile 158	-	insertion
Asp 195	Glu 195	conflict

AL: 2 - 212 (UniProt: Q8IAX6)

PDB	External Database	Details
His 19	Arg 19	conflict
Arg 20	His 20	conflict
Cys 201	Arg 201	conflict

AN: 5 - 150 (UniProt: Q8ILE8)

PDB	External Database	Details
-	Lys 11	deletion

AK: 1 - 201 (UniProt: Q8IJZ7)

PDB	External Database	Details
Ala 109	Tyr 109	conflict

AR: 5 - 293 (UniProt: Q8ILL3)

PDB	External Database	Details
-	Lys 292	deletion

AW: 4 - 154 (UniProt: Q8IDI5)
AW: 4 - 215 (PDB: 3JBN)

Contents of the asymmetric unit

Polymers	Number of chains	78
	Total formula weight	2889425.6
All*	Total formula weight	2889425.6

*Water molecules are not included.