3JAL
Cryo-EM structure of GMPCPP-microtubule co-polymerized with EB3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E, J, C, L, A... | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 6 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (pig) | Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain |
2 | F, G, D, I, B... | Tubulin beta chain | polymer | 445 | 49907.8 | 6 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (pig) | Beta-tubulin |
3 | N, M | Microtubule-associated protein RP/EB family member 3 | polymer | 203 | 22865.2 | 2 | UniProt (Q9UPY8) Pfam (PF00307) In PDB | Homo sapiens (human) | EB1 protein family member 3, EBF3, End-binding protein 3, EB3, RP3 |
4 | A, K, E, J, C... | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 6 | Chemie (GTP) | |||
5 | A, K, E, J, C... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
6 | B, H, F, G, D... | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 6 | Chemie (G2P) |
Sequence modifications
N, M: 1 - 200 (UniProt: Q9UPY8)
PDB | External Database | Details |
---|---|---|
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 14 |
Total formula weight | 646403.7 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 6412.2 | |
All* | Total formula weight | 652815.9 |