3JA8

Cryo-EM structure of the MCM2-7 double hexamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (2)	Minichromosome Maintenance 2	polymer	868	98911.5	1	UniProt (P29469) Pfam (PF12619) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855)	Saccharomyces cerevisiae S288c (yeast)	DNA replication licensing factor MCM2
2	B (3)	Minichromosome Maintenance 3	polymer	971	107653.5	1	UniProt (P24279) Pfam (PF22207) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855)	Saccharomyces cerevisiae S288c (yeast)	DNA replication licensing factor MCM3
3	C (4)	Minichromosome Maintenance 4	polymer	933	105138.4	1	UniProt (P30665) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21128)	Saccharomyces cerevisiae S288c (yeast)	DNA replication licensing factor MCM4
4	D (5)	Minichromosome Maintenance 5	polymer	775	86505.7	1	UniProt (P29496) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21933)	Saccharomyces cerevisiae S288c (yeast)	Minichromosome maintenance protein 5
5	E (6)	Minichromosome Maintenance 6	polymer	1017	113110.2	1	UniProt (P53091) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF18263)	Saccharomyces cerevisiae S288c (yeast)	DNA replication licensing factor MCM6
6	F (7)	Minichromosome Maintenance 7	polymer	845	95049.9	1	UniProt (P38132) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855)	Saccharomyces cerevisiae S288c (yeast)	DNA replication licensing factor MCM7
7	G, H, I, J, K... (2, 3, 4, 5, 6...)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	6	Chemie (ADP)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	606369.2
Non-Polymers*	Number of molecules	6
	Total formula weight	2563.2
All*	Total formula weight	608932.4

*Water molecules are not included.