3J8Y
High-resolution structure of ATP analog-bound kinesin on microtubules
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (K) | Kinesin-1 heavy chain | polymer | 349 | 39238.1 | 1 | UniProt (P33176) Pfam (PF00225) | Homo sapiens (human) | Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC |
| 2 | B (A) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 1 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (pig) | Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain |
| 3 | C (B) | Tubulin beta-2B chain | polymer | 445 | 49983.8 | 1 | UniProt (F2Z5B2) | Sus scrofa (pig) | |
| 4 | D (K) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 5 | E (K) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 7 | G (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) |
Sequence modifications
K: 1 - 349 (UniProt: P33176)
B: 1 - 455 (UniProt: F2Z5B2)
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | Cys 7 | conflict |
| Ala 168 | Cys 168 | conflict |
| Ser 174 | Cys 174 | conflict |
| Ser 330 | Cys 330 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 203 | Cys 201 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 139426.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1497.9 | |
| All* | Total formula weight | 140924.3 |
