3J8Y
High-resolution structure of ATP analog-bound kinesin on microtubules
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (K) | Kinesin-1 heavy chain | polymer | 349 | 39238.1 | 1 | UniProt (P33176) Pfam (PF00225) | Homo sapiens (human) | Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC |
| 2 | B (A) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 1 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (pig) | Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain |
| 3 | C (B) | Tubulin beta-2B chain | polymer | 445 | 49983.8 | 1 | UniProt (F2Z5B2) | Sus scrofa (pig) | |
| 4 | D (K) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 5 | E (K) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 6 | F (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 7 | G (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) |
Sequence modifications
K: 1 - 349 (UniProt: P33176)
B: 1 - 455 (UniProt: F2Z5B2)
| PDB | External Database | Details |
|---|---|---|
| Ser 7 | Cys 7 | conflict |
| Ala 168 | Cys 168 | conflict |
| Ser 174 | Cys 174 | conflict |
| Ser 330 | Cys 330 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 203 | Cys 201 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 139426.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1497.9 | |
| All* | Total formula weight | 140924.3 |
