3IYZ

Structure of Aquaporin-4 S180D mutant at 10.0 A resolution from electron micrograph

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Aquaporin-4	polymer	340	36595.1	1	UniProt (P47863) Pfam (PF00230)	Rattus norvegicus (rat)	AQP-4, WCH4, Mercurial-insensitive water channel, MIWC

Sequence modifications

A: 23 - 323 (UniProt: P47863)

PDB	External Database	Details
Met -16	-	expression tag
Pro -15	-	expression tag
Arg -14	-	expression tag
Gly -13	-	expression tag
Ser -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
Gly -5	-	expression tag
Met -4	-	expression tag
Ala -3	-	expression tag
Ser -2	-	expression tag
Met -1	-	expression tag
Thr 0	-	expression tag
Gly 1	-	expression tag
Gly 2	-	expression tag
Gln 3	-	expression tag
Gln 4	-	expression tag
Met 5	-	expression tag
Gly 6	-	expression tag
Arg 7	-	expression tag
Asp 8	-	expression tag
Leu 9	-	expression tag
Tyr 10	-	expression tag
Asp 11	-	expression tag
Asp 12	-	expression tag
Asp 13	-	expression tag
Asp 14	-	expression tag
Lys 15	-	expression tag
Asp 16	-	expression tag
Pro 17	-	expression tag
Ser 18	-	expression tag
Ser 19	-	expression tag
Arg 20	-	expression tag
Ser 21	-	expression tag
Ile 22	-	expression tag
Asp 180	Ser 180	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36595.1
All*	Total formula weight	36595.1

*Water molecules are not included.