3IWN

Co-crystal structure of a bacterial c-di-GMP riboswitch

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	C-di-GMP riboswitch	polymer	93	30087.0	2
2	C, D	U1 small nuclear ribonucleoprotein A	polymer	91	10552.3	2	UniProt (P09012) Pfam (PF00076) In PDB	Homo sapiens (human)	U1 snRNP protein A, U1A protein, U1-A
3	A, B	9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)	non-polymer		690.4	2	Chemie (C2E)

Sequence modifications

C, D: 801 - 891 (UniProt: P09012)

PDB	External Database	Details
His 826	Tyr 31	engineered mutation
Arg 831	Gln 36	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	81278.6
Non-Polymers*	Number of molecules	2
	Total formula weight	1380.8
All*	Total formula weight	82659.5

*Water molecules are not included.