3IVA
Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half with AdoHcy bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine synthase | polymer | 579 | 65175.5 | 1 | UniProt (P13009) Pfam (PF02607) Pfam (PF02310) Pfam (PF02965) | Escherichia coli | 5-methyltetrahydrofolate--homocysteine methyltransferase, Methionine synthase, vitamin-B12-dependent, MS |
| 2 | B (A) | COBALAMIN | non-polymer | 1330.4 | 1 | Chemie (B12) | |||
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | D, E, F, G (A) | NITRATE ION | non-polymer | 62.0 | 4 | Chemie (NO3) | |||
| 5 | H (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 649 - 1227 (UniProt: P13009)
| PDB | External Database | Details |
|---|---|---|
| Cys 690 | Ile 690 | engineered mutation |
| Cys 743 | Gly 743 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 65175.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1962.8 | |
| All* | Total formula weight | 67138.3 |
